Epiduo Gel 0.1% / 2.5%


Epiduo Gel Galderma
0.1% Aldapene / 2.5% Benzoyl Peroxide

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What is Epiduo Gel?


Think of Epiduo Gel as a nightmare for your breakouts. It is the most prescribed branded topical acne agent in the world.

Epiduo Gel is the only antibiotic-free topical acne treatment with a fixed dose combination of 0.1% adapalene and 2.5% benzoyl peroxide. It helps clear up the breakouts you have now and helps prevent future pimples from forming. It also comes in a convenient pump, so treating breakouts can quickly become a part of your everyday routine.

Benzoyl peroxide is one of the two effective medicines in Epiduo Gel. It’s an antimicrobial which kills the bacteria that lead to breakouts and helps prevent pimples from coming back.

Adapalene is a type of retinoid, and the other medicine in Epiduo Gel. It unclogs blocked pores, helping to stop acne from forming under the skin’s surface and decreasing the redness, swelling and inflammation associated with pimples.

Having both ingredients in a single treatment could also mean fewer co-pays. Use a pea-sized amount on the affected areas daily, and you may only need a refill once every 3 months.

Some people using Epiduo Gel experience redness, scaling, dryness, stinging and/or burning—if that happens and it bothers you, get in touch with your doctor.

Using Epiduo Gel

Two simple steps – that’s all it takes to get your Epi•Do•Over happening.


When you wake up, or just before bedtime, wash your face with a gentle, non-soap cleanser, such as Cetaphil® DERMACONTROL™ Oil Control Foam Wash. Gently pat your face dry with a soft towel, don’t scrub it.


Using a pea-sized amount, apply a thin layer of antibiotic-free Epiduo Gel to each of the affected areas of your face (e.g., forehead, chin, each cheek). Avoid the areas around your eyes and lips.

You may also use a gentle moisturizer on your face afterward, ideally one with SPF protection during the day.

Remember, you won’t speed up the process by using more. Epiduo Gel will work best if you use it as directed.

What to Expect

Expect more from your treatment. Like results.

The dual action of Epiduo® (adapalene and benzoyl peroxide) Gel 0.1%/2.5% will give you results. It’s been proven safe and effective for short- and long-term acne treatment. Clinical trials with thousands of patients showed that many people’s breakouts visibly improved and continued to get better with consistent treatment.

Even when your breakouts are under control, Epiduo Gel is safe to use, as recommended by a doctor, to keep your skin on the right track.

As with most acne treatments, Epiduo Gel may come with mild side effects. If your skin is irritated at first, you should see improvements after the first couple of weeks. Typical side effects associated with short-term and long-term use of Epiduo Gel are redness, scaling, dryness, stinging and burning where applied. A non-comedogenic moisturizer such as Cetaphil® DERMACONTROL™ Oil Control Moisturizer SPF 30 can help if your skin becomes dry. Unless major discomfort occurs, it’s best to keep using Epiduo Gel to make sure you’re on the right path. But don’t hesitate to talk to your doctor if you have major discomfort or if you have any questions or issues at all.


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